Different GPU Vendors in the same Rig

hi all,

Now in my rig i have 2xMSI rx480 gaming X 8gb and 1xMSI rx580 gaming X+ 8gb and works smoothly (mining with stock rom yet and 17.5.2 from amd site).

The question is that if i add 3x Sapphire Radeon Nitro + RX 580 8GB the rig will work fine? in other words is it possible to work with 2 different vendors in the same rig ( msi + sapphire )?

Thanks in advance !